The Challenge: Capping, Surface Softening & Caking
High-dose joint caplets often suffer from tablet capping, surface softening, and caking. In high-hygroscopic MSM & Glucosamine compression, moisture is the driving risk: once water vapor is absorbed during granulation, compression, or storage, moisture degradation directly threatens tablet integrity and label performance.
Manufacturing Controls That Prevent Moisture Degradation
Our contract manufacturing line combines fluid-bed granulation with cleanroom humidity controls below 20% RH to eliminate moisture degradation during production:
- Fluid-bed granulation keeps moisture-sensitive actives stable through a controlled, consistent granulation step.
- Cleanroom humidity controls (<20% RH) protect the compressed caplets from re-absorption from the moment of compression until primary packaging.
This approach is built for formulations in our Glucosamine Hub and MSM Hub.
Key Takeaways
- Fluid-bed granulation plus cleanroom humidity control (<20% RH) eliminate moisture degradation in contract manufacturing.
- The control strategy is purpose-built for high-dose MSM & Glucosamine joint caplets.
- Contact our R&D engineers for a formula feasibility audit and factory quote for your joint health line.